Plasmapheresis in heparin-induced thrombocytopenia and thrombosis.

Treating heparin-induced thrombocytopenia. The unconventional way!

Heparin-induced thrombocytopenia HIT is a potentially devastating complication of heparin therapy. The severe form of HIT has been associated with both venous and arterial thrombosis manifested by myocardial infarction, cerebrovascular occlusion, skin necrosis or limb ischemia. Several agents are now available as alternatives to heparin in patients with suspected HIT, including the thrombin spe...

نشانگان آنتی فسفولیپید

Antiphospholipid syndrome is an autoimmune condition characterized by recurrent vascular thrombosis, pregnancy loss and thrombocytopenia associated with moderate to high levels of antiphospholipid antibodies. Most of clinical features are results of thrombotic phenomena. The pathophysiologic basis ot this syndrome is still unknown. the diagnosis of this syndrome is made by combination of clinic...

Heparin induced thrombocytopenia

Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...

eComment: Plasmapheresis for near-fatal heparin-induced thrombocytopenia.

Heparin-induced thrombocytopenia as a cause of prolonged low platelet count in a patient with thrombotic thrombocytopenic purpura treated with plasmapheresis.

Thrombotic thrombocytopenic purpura (TTP) is a rare disorder belonging to thrombotic microangiopathies (TMA) and is caused by functional deficiency of the ADAMTS-13 metalloproteinase. Plasma exchange (PE) remains the treatment of choice in this disease. Here, were describe the case of a patient who apparently recovered from TTP following multiple sessions of PE, but remained thrombocytopenic. C...